He earned his bachelor of medicine, bachelor of surgery degree from the University of Witwatersrand in Johannesburg, South Africa. After graduating, he completed his internship at Baragwanath Hospital in Johannesburg and his residency at JohannesburgHospital. His fellowships were conducted at the Johannesburg Hospital Liver Unit and the National Institutes of Health in Maryland and the University of Minnesota (United States).
Dr. Dusheiko's research interests include the management and treatment of hepatitis B and C and small hepatocellular carcinoma; he has a special interest in research in viral hepatitis, focused on viral genotyping, applied molecular virology, the natural history of chronic viral hepatitis, and antiviral therapies. He has served on editorial boards for the Journal of Viral Hepatitis, Hepatology, and Best Practice and Research: Clinical Gastroenterology, GUT among others, and is the author of more than 300 published articles. A member of several organizations, including IASL, AASLD, and EASL, he is a fellow of the Royal College of Physicians, the Royal College of Physicians of South Africa, and the Royal College of Physicians of Edinburgh. He served as Educational Councilor on the Governing Board of the European Association for the Study of the Liver for 4 years. He was the recipient of the 2014 EASL recognition award.