Douglas Wallace: Mitochondrial Toxicity
Douglas Wallace, PhD was till recently Director of the Center for Molecular and Mitochondrial Medicine and Genetics at the University of California, Irvine and a Donald Bren professor of Molecular Medicine and Professor of Biological Chemistry and of Ecology and Evolutionary Biology at the University of California, Irvine
Earlier this year he moved to the University of Pennsylvania where he is the director of the Center of Mitochondrial and Epigenomic Medicine and Porfessor at the department of Pathology and Laboratory Medicine.
He has been working on human and mammalian mitochondrial genetics for many years. He reported the first maternally inherited mtDNA disease (Leber Hereditary Optic Neuropathy). His research focuses on studying the relationship between somatic mtDNA mutations and the aging process in general and age-related diseases.