Prof. Nicholas Paton trained in Medicine and Infectious Diseases in Cambridge, Sydney and London, and in Epidemiology at the London School of Hygiene and Tropical Medicine. From 1997 to 2005 he worked as Head of Department at the National HIV Referral Centre in Singapore and, in addition to clinical care responsibilities, developed a Centre for Research in HIV and Communicable Diseases. He then returned to the UK to take up a position at the MRC Clinical Trials Unit (MRC CTU) leading large scale HIV treatment trials such as PIVOT and EARNEST (on which he is the Chief Investigator), as well as working with international research networks such as INSIGHT and NEAT.  In 2011 he moved from the UK back to Singapore to take up a Chair of infectious Diseases at the National University of Singapore where he is working on a programme of TB research focused on developing novel endpoints for TB trials and on evaluating new TB drug combinations.