Mario Roederer, PhD

Mario Roederer, PhD

Mario Roederer, PhD

Mario Roederer, PhD, is a Senior Investigator at the Vaccine Research Center at the National Institutes of Health.  He leads the ImmunoTechnology Section, and also directs the Flow Cytometry Core and the Nonhuman Primate Immunogenicity Core. 

Dr. Roederer has a BS in Chemistry from Harvey Mudd College, a PhD in Cell Biology from Carnegie Mellon, and postdoctoral training with Dr. Leonard Herzenberg at Stanford University.  He has co-authored six patents, five software titles in world-wide use, and more than 300 papers with over 28,000 citations.
His research combines advanced technology development in the setting of single cell analysis (integrating both flow cytometry and transcriptomics), with basic T and B cell immunology. Over the past two decades, he led the effort to the develop the state-of-the-art 30+ color flow cytometry. Basic research projects include T cell dynamics during HIV or SIV infection; the definition of the complete repertoire of functions of elicited by vaccines and pathogens; characterization of memory stem cells for generation and maintenance of long-term T cell memory; mucosal delivery of vaccines for use in influenza, RSV, and TB; and understanding the antigenic heterogeneity of HIV/SIV Env to develop protective antibodies.