Jamie N. Justice, Ph.D., is an Instructor in Internal Medicine Section on Gerontology and Geriatrics, and Sticht Center of Healthy Aging and Alzheimer’s Prevention at Wake Forest School of Medicine. Dr. Justice’s research interests are in the integrative (biologic to systemic) mechanisms that mediate aging and their functional consequences (e.g., the role of cellular senescence), and interventions to improve healthspan – i.e. prevent or delay adverse functional decline, and the onset of age-related disability and chronic diseases. Her research experience includes translational experimental approaches that span preclinical studies in animal models of aging to clinical trials investigating agents that target the biologic mechanisms of aging. This work includes efforts to launch the proposed groundbreaking clinical trial, Targeting Aging with MEtformin (TAME), which is designed to be a prototype for future trials to test promising agents identified by geroscience (biology of aging) research.