Dr. Thuy Le is an Associate Professor of Medicine at Duke University, an Adjunct Associate Professor of Medicine at the University of Hawaii and a Visiting Fellow at the Oxford University Clinical Research Unit in Vietnam. She leads a research program to improve HIV clinical outcomes in Southeast Asia by mitigating HIV drug resistance development and developing novel diagnostics and treatment strategies for a leading HIV-associated opportunistic infection caused by the dimorphic fungus Talaromyces marneffei. She led the IVAP clinical trial in talaromycosis treatment that demonstrated the superiority of amphotericin B over itraconazole in reducing deaths. The study has redefined international treatment recommendations for this important endemic mycosis and calls for amphotericin to be made widely available in Asia. She is a Member of the Program Committee for the Asia Pacific AIDS and Co-Infection Conference, Member of several WHO Guidelines Committees on Management of HIV, Member of the NIH/CDC/HIVMA/IDSA Guidelines Committee on Opportunistic Infections, and a Coordinator of the European Confederation of Medical Mycology Guidelines for Endemic Mycoses. She has published in the New England Journal of Medicine, Lancet, Clinical Infectious Diseases, AIDS, and Antiviral Therapy.